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Two Distinct Categories of Focal Deletions in Cancer Genomes.

One of the key questions about genomic alterations in cancer is whether they are functional in the sense of contributing to the selective advantage of tumor cells. The frequency with which an alteration occurs might reflect its ability to increase cancer cell growth, or alternatively, enhanced insta...

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Bibliografiske detaljer
Principais autores: Megha Rajaram, Jianping Zhang, Tim Wang, Jinyu Li, Cem Kuscu, Huan Qi, Mamoru Kato, Vladimir Grubor, Robert J Weil, Aslaug Helland, Anne-Lise Borrenson-Dale, Kathleen R Cho, Douglas A Levine, Alan N Houghton, Jedd D Wolchok, Lois Myeroff, Sanford D Markowitz, Scott W Lowe, Michael Zhang, Alex Krasnitz, Robert Lucito, David Mu, R Scott Powers
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3689739?pdf=render
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