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Involvement of caspase-dependent activation of cytosolic phospholipase A(2) in tumor necrosis factor-induced apoptosis

Tumor necrosis factor (TNF)-induced apoptosis is mediated by caspases, which are cysteine proteases related to interleukin 1β-converting enzyme. We report here that TNF-induced activation of caspases results in the cleavage and activation of cytosolic phospholipase A(2) (cPLA(2)) and that activated...

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Detalhes bibliográficos
Main Authors: Wissing, Dorte, Mouritzen, Helle, Egeblad, Mikala, Poirier, Guy G., Jäättelä, Marja
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24633/
https://ncbi.nlm.nih.gov/pubmed/9144192
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