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Biological Pathway-Derived TMB Robustly Predicts the Outcome of Immune Checkpoint Blockade Therapy

Although immune checkpoint blockade (ICB) therapies have achieved great progress, the patient response varies among cancers. In this study, we analyzed the potential genomic indicators contributing to ICB therapy response. The results showed that high tumor mutation burden (TMB) failed to predict re...

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Bibliografske podrobnosti
Principais autores: Ya-Ru Miao, Chun-Jie Liu, Hui Hu, Mei Yang, An-Yuan Guo
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2022-09-01
Serija:Cells
Teme:
Online dostop:https://www.mdpi.com/2073-4409/11/18/2802
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