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Biological Pathway-Derived TMB Robustly Predicts the Outcome of Immune Checkpoint Blockade Therapy

Although immune checkpoint blockade (ICB) therapies have achieved great progress, the patient response varies among cancers. In this study, we analyzed the potential genomic indicators contributing to ICB therapy response. The results showed that high tumor mutation burden (TMB) failed to predict re...

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書誌詳細
主要な著者: Ya-Ru Miao, Chun-Jie Liu, Hui Hu, Mei Yang, An-Yuan Guo
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2022-09-01
シリーズ:Cells
主題:
オンライン・アクセス:https://www.mdpi.com/2073-4409/11/18/2802
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