Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that results from slow axon growth. This impairs axonal regeneration and causes...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	eLife Sciences Publications Ltd 2021-01-01
Sarja:	eLife
Aiheet:	nerve regeneration schwann cell c-Jun aging chronic denervation repair cell
Linkit:	https://elifesciences.org/articles/62232
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