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Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice.

When 5-lipoxygenase (5-LO) is inhibited, roughly half of the CNS effect of the prototypic endocannabinoid anandamide (AEA) is lost. Therefore, we decided to investigate whether inhibiting this enzyme would influence physiological functions classically described as being under control of the endocann...

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Bibliografiske detaljer
Principais autores: Luciana M Leo, Suellen Almeida-Corrêa, Claudio A Canetti, Olavo B Amaral, Fernando A Bozza, Fabricio A Pamplona
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-01-01
Serier:PLoS ONE
Online adgang:https://doi.org/10.1371/journal.pone.0085009
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