Coreceptors and TCR Signaling – the Strong and the Weak of It
The T-cell coreceptors CD4 and CD8 have well-characterized and essential roles in thymic development, but how they contribute to immune responses in the periphery is unclear. Coreceptors strengthen T-cell responses by many orders of magnitude – beyond a million-fold according to some estimates – but...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2020-10-01
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| Edice: | Frontiers in Cell and Developmental Biology |
| Témata: | |
| On-line přístup: | https://www.frontiersin.org/article/10.3389/fcell.2020.597627/full |
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