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Coreceptors and TCR Signaling – the Strong and the Weak of It

The T-cell coreceptors CD4 and CD8 have well-characterized and essential roles in thymic development, but how they contribute to immune responses in the periphery is unclear. Coreceptors strengthen T-cell responses by many orders of magnitude – beyond a million-fold according to some estimates – but...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Alexander M. Mørch, Štefan Bálint, Ana Mafalda Santos, Simon J. Davis, Michael L. Dustin
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Frontiers Media S.A. 2020-10-01
Цуврал:Frontiers in Cell and Developmental Biology
Нөхцлүүд:
Онлайн хандалт:https://www.frontiersin.org/article/10.3389/fcell.2020.597627/full
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