Phylogenomics-guided discovery of a novel conserved cassette of short linear motifs in BubR1 essential for the spindle checkpoint

The spindle assembly checkpoint (SAC) maintains genomic integrity by preventing progression of mitotic cell division until all chromosomes are stably attached to spindle microtubules. The SAC critically relies on the paralogues Bub1 and BubR1/Mad3, which integrate kinetochore–spindle attachment stat...

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Xehetasun bibliografikoak

Egile Nagusiak:	Eelco Tromer, Debora Bade, Berend Snel, Geert J. P. L. Kops
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	The Royal Society 2016-01-01
Saila:	Open Biology
Gaiak:	kinetochore mitosis evolutionary genomics short linear motif spindle checkpoint
Sarrera elektronikoa:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160315
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!