Codice QR

Gene-body DNA methylation of ONECUT2 predicts its expression and prostate cancer aggressiveness in needle biopsies

Abstract Background ONECUT2 is a lineage plasticity driver and therapeutic target in aggressive prostate cancer (PCa). This study investigated whether ONECUT2 gene-body DNA methylation regulates its expression and assessed its potential as a biomarker in clinical specimens. Methods We analyzed assoc...

Descrizione completa

Salvato in:
Autori principali: Yohei Sekino, Hong-Tao Li, Masatomo Kaneko, Yuta Inoue, Lorenzo Storino Ramacciotti, Rongying Lu, Zhenzhong Deng, Xinyi Zhou, Michelle Mingxue Song, Aditya Desai, Mingda Jin, Wei Guo, Xiaojing Yang, Jeffrey Bhasin, Nobuyuki Hinata, Michael R. Freeman, Inderbir Gill, Manju Aron, Steven Yong Cen, Andre Luis Abreu, Gangning Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2026-01-01
Serie:Biomarker Research
Soggetti:
ONECUT2
Prostate cancer
Gene-body
DNA methylation
Gene expression
Aggressive prostate cancer
Accesso online:https://doi.org/10.1186/s40364-026-00890-7
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!

Documenti analoghi