Large scale RNAi reveals the requirement of nuclear envelope breakdown for nuclear import of human papillomaviruses.
A two-step, high-throughput RNAi silencing screen was used to identify host cell factors required during human papillomavirus type 16 (HPV16) infection. Analysis of validated hits implicated a cluster of mitotic genes and revealed a previously undetermined mechanism for import of the viral DNA (vDNA...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2014-05-01
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| Serie: | PLoS Pathogens |
| Accesso online: | http://europepmc.org/articles/PMC4038628?pdf=render |
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