Combined HRAS and NRAS ablation induces a RASopathy phenotype in mice
Abstract Background HRASKO/NRASKO double knockout mice exhibit exceedingly high rates of perinatal lethality due to respiratory failure caused by a significant lung maturation delay. The few animals that reach adulthood have a normal lifespan, but present areas of atelectasis mixed with patches of e...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2024-06-01
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| Seria: | Cell Communication and Signaling |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s12964-024-01717-4 |
| Etykiety: |
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