Combined HRAS and NRAS ablation induces a RASopathy phenotype in mice
Abstract Background HRASKO/NRASKO double knockout mice exhibit exceedingly high rates of perinatal lethality due to respiratory failure caused by a significant lung maturation delay. The few animals that reach adulthood have a normal lifespan, but present areas of atelectasis mixed with patches of e...
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| Автори: | , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2024-06-01
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| Серія: | Cell Communication and Signaling |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s12964-024-01717-4 |
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