Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors
Abstract: Activated factor XIIa (FXIIa) is a serine protease that has received a great deal of interest in recent years as a potential target for the development of new antithrombotics. Despite the strong interest in obtaining structural information, only the structure of the FXIIa catalytic domain...
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| Principais autores: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2018-03-01
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| 叢編: | Blood Advances |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2473952920310788 |
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