Structural shifts in TolC facilitate Efflux-Mediated β-lactam resistance
Abstract Efflux-mediated β-lactam resistance is a major public health concern, reducing the effectiveness of β-lactam antibiotics against many bacteria. Structural analyses show the efflux protein TolC in Gram-negative bacteria acts as a channel for antibiotics, impacting bacterial susceptibility an...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2024-08-01
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| coleção: | Communications Biology |
| Acesso em linha: | https://doi.org/10.1038/s42003-024-06750-0 |
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