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Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle Pathway.

Trehalose 6,6'-dimycolate (TDM), a cord factor of Mycobacterium tuberculosis (Mtb), is an important regulator of immune responses during Mtb infections. Macrophages recognize TDM through the Mincle receptor and initiate TDM-induced inflammatory responses, leading to lung granuloma formation. Althoug...

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Principais autores: Wook-Bin Lee, Ji-Seon Kang, Ji-Jing Yan, Myeong Sup Lee, Bo-Young Jeon, Sang-Nae Cho, Young-Joon Kim
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2012-01-01
סדרה:PLoS Pathogens
גישה מקוונת:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22496642/?tool=EBI
תגים: הוספת תג
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