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Mouse Mincle: Characterization as a Model for Human Mincle and Evolutionary Implications

Mincle, the macrophage-inducible C-type lectin also known as CLEC-4E, binds to the mycobacterial glycolipid trehalose dimycolate and initiates a signaling cascade by serving as a receptor for Mycobacterium tuberculosis and other pathogenic mycobacterial species. Studies of the biological functions o...

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Principais autores: Neela D. S. Rambaruth, Sabine A. F. Jégouzo, Hayley Marlor, Maureen E. Taylor, Kurt Drickamer
格式: Artigo
語言:Inglês
出版: MDPI AG 2015-04-01
叢編:Molecules
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在線閱讀:http://www.mdpi.com/1420-3049/20/4/6670
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