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The design and construction of reference pangenome graphs with minigraph

Abstract The recent advances in sequencing technologies enable the assembly of individual genomes to the quality of the reference genome. How to integrate multiple genomes from the same species and make the integrated representation accessible to biologists remains an open challenge. Here, we propos...

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Autores principales: Heng Li, Xiaowen Feng, Chong Chu
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2020-10-01
Colección:Genome Biology
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Acceso en línea:http://link.springer.com/article/10.1186/s13059-020-02168-z
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