Grape Seed Proanthocyanidins Enhance Time-Dependent HO-1 Activation and Improve Redox Homeostasis in Obesity-Induced Hepatic Dysfunction

Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by impaired metabolic flexibility, oxidative stress, and disruption of the temporal coordination of hepatic processes. Obesogenic diets contribute to this dysfunction by altering redox homeostasis and autophagy, thereb...

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Autori principali:	María Zamora-Úbeda, Aina Gironès-Garreta, Julieta Cirasino, Josep M. Del Bas, Jorge R. Soliz-Rueda, Miquel Mulero, Enrique Calvo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2026-06-01
Serie:	Antioxidants
Soggetti:	metabolic dysfunction-associated steatotic liver disease (MASLD) cafeteria diet grape seed proanthocyanidin extract (GSPE) circadian rhythm NRF2/HO-1 axis oxidative stress
Accesso online:	https://www.mdpi.com/2076-3921/15/6/734
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