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Osteoblasts and osteoclasts: an important switch of tumour cell dormancy during bone metastasis

Abstract Bone metastasis occurs when tumour cells dissociate from primary tumours, enter the circulation (circulating tumour cells, CTCs), and colonize sites in bone (disseminated tumour cells, DTCs). The bone marrow seems to be a particularly dormancy-inducing environment for DTCs, yet the mechanis...

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Bibliografiske detaljer
Principais autores: Rongchen Dai, Mengfan Liu, Xincheng Xiang, Zhichao Xi, Hongxi Xu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-10-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
Online adgang:https://doi.org/10.1186/s13046-022-02520-0
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