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Tumor removal limits prostate cancer cell dissemination in bone and osteoblasts induce cancer cell dormancy through focal adhesion kinase

Abstract Background Disseminated tumor cells (DTCs) can enter a dormant state and cause no symptoms in cancer patients. On the other hand, the dormant DTCs can reactivate and cause metastases progression and lethal relapses. In prostate cancer (PCa), relapse can happen after curative treatments such...

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Autori principali: Ruihua Liu, Shang Su, Jing Xing, Ke Liu, Yawei Zhao, Mary Stangis, Diego P. Jacho, Eda D. Yildirim-Ayan, Cara M. Gatto-Weis, Bin Chen, Xiaohong Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2023-10-01
Serie:Journal of Experimental & Clinical Cancer Research
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Accesso online:https://doi.org/10.1186/s13046-023-02849-0
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