Tumor removal limits prostate cancer cell dissemination in bone and osteoblasts induce cancer cell dormancy through focal adhesion kinase

Abstract Background Disseminated tumor cells (DTCs) can enter a dormant state and cause no symptoms in cancer patients. On the other hand, the dormant DTCs can reactivate and cause metastases progression and lethal relapses. In prostate cancer (PCa), relapse can happen after curative treatments such...

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Bibliografische Detailangaben

Hauptverfasser:	Ruihua Liu, Shang Su, Jing Xing, Ke Liu, Yawei Zhao, Mary Stangis, Diego P. Jacho, Eda D. Yildirim-Ayan, Cara M. Gatto-Weis, Bin Chen, Xiaohong Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-10-01
Schriftenreihe:	Journal of Experimental & Clinical Cancer Research
Schlagworte:	Prostate cancer Bone metastases; tumor removal Dormancy Osteoblasts Mitochondria FAK
Online-Zugang:	https://doi.org/10.1186/s13046-023-02849-0
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