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Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity

Poly(ADP-ribose) polymerase-1 (PARP-1) is the guardian of the genome acting as a sentinel for genomic damage. However, PARP-1 is also mediator of cell death after ischemia-reperfusion injury, glutamate excitotoxicity, and various inflammatory processes. The biochemistry underlying PARP-1-mediated ce...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Seong-Woon Yu, Hongmin Wang, Ted M Dawson, Valina L Dawson
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2003-12-01
Sarja:Neurobiology of Disease
Linkit:http://www.sciencedirect.com/science/article/pii/S0969996103001517
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