Laboratory Evolution Experiments Help Identify a Predominant Region of Constitutive Stable DNA Replication Initiation

ABSTRACT The bacterium Escherichia coli can initiate replication in the absence of the replication initiator protein DnaA and/or the canonical origin of replication oriC in a ΔrnhA background. This phenomenon, which can be primed by R-loops, is called constitutive stable DNA replication (cSDR). Whet...

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Auteurs principaux:	Reshma T. Veetil, Nitish Malhotra, Akshara Dubey, Aswin Sai Narain Seshasayee
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology 2020-02-01
Collection:	mSphere
Sujets:	DNA replication DnaA R-loops constitutive stable DNA replication evolution gene expression
Accès en ligne:	https://journals.asm.org/doi/10.1128/mSphere.00939-19
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