Modification of aggregation-prone regions of Arabidopsis glutamyl-tRNA reductase leads to increased stability while maintaining enzyme activity
The aggregation-prone region (APR) is a hydrophobic polypeptide motif that promotes protein aggregation, most commonly in the unfolded or misfolded state. It has been described that chaperones can shield the APRs of proteins, thereby preventing aggregate formation during de novo protein synthesis an...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2025-03-01
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| coleção: | Frontiers in Plant Science |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fpls.2025.1556843/full |
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