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Modification of aggregation-prone regions of Arabidopsis glutamyl-tRNA reductase leads to increased stability while maintaining enzyme activity

The aggregation-prone region (APR) is a hydrophobic polypeptide motif that promotes protein aggregation, most commonly in the unfolded or misfolded state. It has been described that chaperones can shield the APRs of proteins, thereby preventing aggregate formation during de novo protein synthesis an...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Shuiling Ji, Peng Wang, Bernhard Grimm
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Frontiers Media S.A. 2025-03-01
Цуврал:Frontiers in Plant Science
Нөхцлүүд:
Онлайн хандалт:https://www.frontiersin.org/articles/10.3389/fpls.2025.1556843/full
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