Anticonvulsant activity of atorvastatin against seizure induced by pentylenetetrazole and maximal electroshock in mice
Statins are inhibitors of HMG-CoA reductase and inhibit cellular synthesis of cholesterol and isoprenoids. Studies have previously demonstrated the anti-inflammatory and vasoprotective effects of statins on cultured brain cells (astrocytes and microglia) and endothelial cells. Atorvastatin also prol...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Shiraz University of Medical Sciences
2015-03-01
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| Series: | Trends in Pharmaceutical Sciences |
| Assuntos: | |
| Acceso en liña: | http://tips.sums.ac.ir/index.php/TiPS/article/view/20/18 |
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