Anticonvulsant effects of pentoxifylline on seizures induced by pentylenetetrazole and maximal electroshock in male mice: The role of the nitrergic pathway

Introduction: Epilepsy remains a challenge, with one-third of patients experiencing refractory seizures despite current anti-seizure medications. The nitrergic system, which involves nitric oxide (NO) and NO synthase (NOS) enzymes, plays a complex role in seizure pathophysiology. Pentoxifylline (PTP...

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Detalhes bibliográficos

Principais autores:	Mohammad Keshavarzi, Moein Ghasemi, Mohammad Amin Manavi, Ahmad Reza Dehpour, Hamed Shafaroodi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-12-01
coleção:	IBRO Neuroscience Reports
Assuntos:	Pentoxifylline Nitric oxide Pentylenetetrazole Maximal electroshock Dose-response
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2667242124001064
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