Aurora A site specific TACC3 phosphorylation regulates astral microtubule assembly by stabilizing γ-tubulin ring complex

Abstract Background Astral microtubules emanating from the mitotic centrosomes play pivotal roles in defining cell division axis and tissue morphogenesis. Previous studies have demonstrated that human transforming acidic coiled-coil 3 (TACC3), the most conserved TACC family protein, regulates format...

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Principais autores:	Resmi Rajeev, Puja Singh, Ananya Asmita, Ushma Anand, Tapas K. Manna
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-12-01
coleção:	BMC Molecular and Cell Biology
Assuntos:	Centrosome Microtubule Mitosis Protein phosphorylation Mitotic spindle
Acesso em linha:	https://doi.org/10.1186/s12860-019-0242-z
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