Efficient production of phenyllactic acid in Escherichia coli via metabolic engineering and fermentation optimization strategies

Phenyllactic acid (PhLA), an important natural organic acid, can be used as a biopreservative, monomer of the novel polymeric material poly (phenyllactic acid), and raw material for various medicines. Herein, we achieved a high-level production of PhLA in Escherichia coli through the application of...

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Principais autores:	Weibin Wu, Maosen Chen, Chenxi Li, Jie Zhong, Rusheng Xie, Zhibin Pan, Junhan Lin, Feng Qi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-08-01
coleção:	Frontiers in Microbiology
Assuntos:	metabolic engineering Escherichia coli phenyllactic acid synthetic biology dissolved oxygen feedback fed-batch
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmicb.2024.1457628/full
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