Ethyl pyruvate reduces organic dust-induced airway inflammation by targeting HMGB1-RAGE signaling

Abstract Background Animal production workers are persistently exposed to organic dust and can suffer from a variety of respiratory disease symptoms and annual decline in lung function. The role of high mobility group box-1 (HMGB1) in inflammatory airway diseases is emerging. Hence, we tested a hypo...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Sanjana Mahadev Bhat, Nyzil Massey, Locke A. Karriker, Baljit Singh, Chandrashekhar Charavaryamath
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2019-02-01
Цуврал:	Respiratory Research
Нөхцлүүд:	Organic dust HMGB1 RAGE Lung inflammation Ethyl pyruvate
Онлайн хандалт:	http://link.springer.com/article/10.1186/s12931-019-0992-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!