ADAM10‐Mediated Proteolytic Remodelling of Signalling and Adhesion Proteins on Brain Cell‐Derived Small Extracellular Vesicles

ABSTRACT Proteases are common components of extracellular vesicles (EVs), yet the extent and functional relevance of ongoing proteolytic activity on EV surfaces remain largely unexplored. Such activity could significantly influence EV function and identity, with likely implications for EV‐mediated s...

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Autori principali:	Christopher C. Reimann, Hermann C. Altmeppen, Tomas Koudelka, Michaela Schweizer, Andreas Tholey, Behnam Mohammadi, Julia Bär, Lesley Cheng, Markus Glatzel, Marina Mikhaylova, Andrew F. Hill
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2026-04-01
Serie:	Journal of Extracellular Biology
Soggetti:	ADAM10 ectodomain shedding extracellular vesicles intercellular communication neurobiology prion protein
Accesso online:	https://doi.org/10.1002/jex2.70129
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