A Natural Glucan from Black Bean Inhibits Cancer Cell Proliferation via PI3K-Akt and MAPK Pathway

A natural α-1,6-glucan named BBWPW was identified from black beans. Cell viability assay showed that BBWPW inhibited the proliferation of different cancer cells, especially HeLa cells. Flow cytometry analysis indicated that BBWPW suppressed the HeLa cell cycle in the G2/M phase. Consistently, RT-PCR...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Peng Li, Yihua Hu, Lingmin Zhan, Jiaqi He, Jingwu Lu, Chunyan Gao, Weijun Du, Aiqin Yue, Jinzhong Zhao, Wuxia Zhang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2023-02-01
Цуврал:	Molecules
Нөхцлүүд:	black bean polysaccharide anti-cancer activity cell cycle arrest PI3K/Akt MAPK
Онлайн хандалт:	https://www.mdpi.com/1420-3049/28/4/1971
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!