A Natural Glucan from Black Bean Inhibits Cancer Cell Proliferation via PI3K-Akt and MAPK Pathway

A natural α-1,6-glucan named BBWPW was identified from black beans. Cell viability assay showed that BBWPW inhibited the proliferation of different cancer cells, especially HeLa cells. Flow cytometry analysis indicated that BBWPW suppressed the HeLa cell cycle in the G2/M phase. Consistently, RT-PCR...

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Huvudupphov:	Peng Li, Yihua Hu, Lingmin Zhan, Jiaqi He, Jingwu Lu, Chunyan Gao, Weijun Du, Aiqin Yue, Jinzhong Zhao, Wuxia Zhang
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2023-02-01
Serie:	Molecules
Ämnen:	black bean polysaccharide anti-cancer activity cell cycle arrest PI3K/Akt MAPK
Länkar:	https://www.mdpi.com/1420-3049/28/4/1971
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