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Activation of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with amines and amino acids

We report the first activation study of the β-class carbonic anhydrase (CA, EC 4.2.1.1) encoded in the genome of the protozoan pathogen Trichomonas vaginalis, TvaCA1. Among 24 amino acid and amine activators investigated, derivatives incorporating a second carboxylic moiety, such as L-Asp, L- and D-...

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Bibliografische Detailangaben
Hauptverfasser: Andrea Angeli, Linda J. Urbański, Vesa P. Hytönen, Seppo Parkkila, Claudiu T. Supuran
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2021-01-01
Schriftenreihe:Journal of Enzyme Inhibition and Medicinal Chemistry
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Online-Zugang:http://dx.doi.org/10.1080/14756366.2021.1897802
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