Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase from Trichomonas vaginalis

We report the biochemical and structural characterisation of a beta-carbonic anhydrase (β-CA) from Trichomonas vaginalis, a unicellular parasite responsible for one of the world’s leading sexually transmitted infections, trichomoniasis. CAs are ubiquitous metalloenzymes belonging to eight evolutiona...

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Autori principali:	Linda J. Urbański, Anna Di Fiore, Latifeh Azizi, Vesa P. Hytönen, Marianne Kuuslahti, Martina Buonanno, Simona M. Monti, Andrea Angeli, Reza Zolfaghari Emameh, Claudiu T. Supuran, Giuseppina De Simone, Seppo Parkkila
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2020-01-01
Serie:	Journal of Enzyme Inhibition and Medicinal Chemistry
Soggetti:	beta carbonic anhydrase trichomonas vaginalis protozoan kinetics crystal structure
Accesso online:	http://dx.doi.org/10.1080/14756366.2020.1774572
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