Tumor-Derived Microvesicles Modulate Antigen Cross-Processing via Reactive Oxygen Species-Mediated Alkalinization of Phagosomal Compartment in Dendritic Cells

Dendritic cells (DCs) are the only antigen-presenting cells able to prime naïve T cells and cross-prime antigen-specific CD8+ T cells. Their functionality is a requirement for the induction and maintenance of long-lasting cancer immunity. Albeit intensively investigated, the in vivo mechanisms under...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Federico Battisti, Chiara Napoletano, Hassan Rahimi Koshkaki, Francesca Belleudi, Ilaria Grazia Zizzari, Ilary Ruscito, Sara Palchetti, Filippo Bellati, Pierluigi Benedetti Panici, Maria Rosaria Torrisi, Giulio Caracciolo, Fabio Altieri, Marianna Nuti, Aurelia Rughetti
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2017-09-01
سلاسل:	Frontiers in Immunology
الموضوعات:	microvesicles dendritic cells antigen-processing phagosome radical oxigen species immune response to cancer
الوصول للمادة أونلاين:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01179/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!