Successful Tarlatamab Rechallenge After Recurrent High-Grade Cytokine Release Syndrome in Chromothripsis-Mediated SCLC: A Case Report

Chromothripsis-mediated SCLC (cSCLC) is a distinct subtype of SCLC characterized by wild-type TP53 and RB1, arising in light- or never-smokers. Although data are limited, cSCLC may be associated with poor response to first-line platinum-based chemotherapy. We report the case of a 60-year-old woman w...

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Principais autores:	Ryan Cheng, MD, Sarah Reddy, MD, Kendra Gee-Rodriguez, PharmD, Rogelyn Harlan, MS, FNP-C, Chetan Vakkalagadda, MD, Jeremy Cetnar, MD, Rebecca Silbermann, MD, Richard T. Maziarz, MD, Rajat Thawani, MD
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2026-06-01
Serija:	JTO Clinical and Research Reports
Teme:	Tarlatamab Cytokine release syndrome Lung cancer in non-smokers Case report
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2666364326000482
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