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Early trajectory of inflammatory cytokines following tarlatamab administration in three advanced SCLC patients

Abstract Tarlatamab, a bispecific T-cell engager (BiTE), effectively activates the immune system but often causes cytokine release syndrome (CRS). To understand the early in vivo cytokine dynamics of post-BiTE therapy, we analyzed serum from three SCLC patients before and after tarlatamab administra...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Takuma Imakita, Kohei Fujita, Yuki Yamamoto, Osamu Kanai, Yuta Okada, Shogo Toyama, Takanori Ito, Issei Oi, Kiminobu Tanizawa
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Springer 2025-11-01
Rangatū:Cancer Immunology, Immunotherapy
Ngā marau:
Urunga tuihono:https://doi.org/10.1007/s00262-025-04243-5
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