FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists.

<h4>Background and objective</h4>Muscarinic acetylcholine receptors (mAChRs) are 7-transmembrane, G protein-coupled receptors that regulate a variety of physiological processes and represent potentially important targets for therapeutic intervention. mAChRs can be stimulated by full and partial orth...

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Autores principales:	Danijela Markovic, Jonathan Holdich, Suleiman Al-Sabah, Rajendra Mistry, Cornelius Krasel, Martyn P Mahaut-Smith, R A John Challiss
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2012-01-01
Colección:	PLoS ONE
Acceso en línea:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0029946&type=printable
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