CircZFAND6 suppresses gastric cancer metastasis and reduces resistance to TKI therapy

Abstract Background Peritoneal metastasis, the most common mode of dissemination in gastric cancer (GC), is characterized by resistance to treatment and a poor prognosis. Accumulating evidence indicates that circular RNAs (circRNAs) play a significant role in tumor progression. However, the role of...

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Autors principals:	Zi-Jian Deng, Li-Ying OuYang, Jian-Ping Guo, Huan-Ting Yao, Jun-Jie Liu, Shu-Li Ma, Dong-Wen Chen, Xian-Zhe Li, Lei Lian, Jun-Sheng Peng, Shi Chen
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-12-01
Col·lecció:	Molecular Cancer
Matèries:	Gastric cancer Metastasis TKI Gefitinib resistance CircRNA Wnt/β-catenin
Accés en línia:	https://doi.org/10.1186/s12943-025-02478-5
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