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Simian virus Large T antigen interacts with the N-terminal domain of the 70 kD subunit of Replication Protein A in the same mode as multiple DNA damage response factors.

Simian virus 40 (SV40) serves as an important model organism for studying eukaryotic DNA replication. Its helicase, Large T-antigen (Tag), is a multi-functional protein that interacts with multiple host proteins, including the ubiquitous ssDNA binding protein Replication Protein A (RPA). Tag recruit...

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Bibliografiske detaljer
Principais autores: Boting Ning, Michael D Feldkamp, David Cortez, Walter J Chazin, Katherine L Friedman, Ellen Fanning
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2015-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0116093&type=printable
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