Phosphatidylcholine-specific B cells are enriched among atypical CD11chigh and CD21low memory B cells in antiphospholipid syndrome

BackgroundPatients with antiphospholipid syndrome (APS) carry an increased risk of thrombosis and adverse pregnancy outcomes due to the presence of antiphospholipid autoantibodies (aPL). However, the pathogenesis of the disease remains incompletely understood regarding various aPL and the role of au...

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Detalhes bibliográficos

Principais autores:	Eduard Nitschke, Van Duc Dang, Hector Rincon-Arevalo, Franziska Szelinski, Jacob Ritter, Eva Schrezenmeier, Tobias Alexander, Tuan Anh Le, Yidan Chen, Annika Wiedemann, Jose-Bernardino Gonzalez, Andreia C. Lino, Ana-Luisa Stefanski, Thomas Dörner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-06-01
coleção:	Frontiers in Immunology
Assuntos:	B cells adaptive immunity antigen-specific B cells APS - antiphospholipid syndrome anti-phospholipid antibodies secondary APS
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1585953/full
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