Phosphatidylcholine-specific B cells are enriched among atypical CD11chigh and CD21low memory B cells in antiphospholipid syndrome

BackgroundPatients with antiphospholipid syndrome (APS) carry an increased risk of thrombosis and adverse pregnancy outcomes due to the presence of antiphospholipid autoantibodies (aPL). However, the pathogenesis of the disease remains incompletely understood regarding various aPL and the role of au...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Eduard Nitschke, Van Duc Dang, Hector Rincon-Arevalo, Franziska Szelinski, Jacob Ritter, Eva Schrezenmeier, Tobias Alexander, Tuan Anh Le, Yidan Chen, Annika Wiedemann, Jose-Bernardino Gonzalez, Andreia C. Lino, Ana-Luisa Stefanski, Thomas Dörner
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-06-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	B cells adaptive immunity antigen-specific B cells APS - antiphospholipid syndrome anti-phospholipid antibodies secondary APS
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1585953/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!