Mitochondrial DNA released from pyroptotic synovial macrophages via DDIT3-mediated mitophagy aggravates osteoarthritis progression

Objective: Emerging evidence has shown that inflammatory synovial macrophage and anabolism-impaired chondrocytes play essential roles in osteoarthritis (OA). The present work aims at uncovering the pathogenic mechanism of how the damage-associated molecular patterns (DAMPs) released from inflammator...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Chang Yang, Jin Ke, Qiongdong Xu, Wei Dong, Wenqian Yu, Yan Wang, Jiawei Wang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2026-01-01
Saila:	Journal of Orthopaedic Translation
Gaiak:	Cartilage degeneration DDIT3 mtDNA release Osteoarthritis Pyroptotic macrophages
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2214031X25001925
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!