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Modulating tumour metabolism enhances gold nanoparticle radiosensitisation in HPV-negative head and neck cancer

Abstract Background Radiotherapy is a major therapeutic modality for locally advanced head and neck cancer. However, the effectiveness of radiotherapy is hindered by resistance mechanisms, most notably hypoxia, leading to unfavourable treatment outcomes. In this study, we investigate the radiosensit...

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Autori principali: Jie Feng, Varun Pathak, Niall M. Byrne, Tongchuan Wang, Cancan Yin, Reinhold J. Medina, Jonathan A. Coulter
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2023-04-01
Serie:Cancer Nanotechnology
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Accesso online:https://doi.org/10.1186/s12645-023-00185-8
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