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β-aminopropionitrile-induced thoracic aortopathy is refractory to cilostazol and sildenafil in mice.

Thoracic aortopathies are life-threatening diseases including aneurysm, dissection, and rupture. Cilostazol, a phosphodiesterase (PDE) 3 inhibitor, and sildenafil, a PDE5 inhibitor, have been used clinically for peripheral arterial disease and erectile dysfunction or pulmonary hypertension, respecti...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Samuel C Tyagi, Sohei Ito, Jacob C Hubbuch, Michael K Franklin, Deborah A Howatt, Hong S Lu, Alan Daugherty, Hisashi Sawada
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2025-01-01
Rangatū:PLoS ONE
Urunga tuihono:https://doi.org/10.1371/journal.pone.0322434
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