Implication of the Transmembrane Domain in the Interleukin 10 Receptor Platform Oligomerisation
Interleukin 10 (IL-10) exerts anti-inflammatory and immune regulatory roles through its fixation to the IL-10 receptor (IL-10R). The two subunits (IL-10Rα and IL-10Rβ) organise themselves to form a hetero-tetramer to induce the activation of the transcription factor STAT3. We analysed the activation...
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| Principais autores: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI AG
2023-05-01
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| 叢編: | Cells |
| 主題: | |
| 在線閱讀: | https://www.mdpi.com/2073-4409/12/10/1361 |
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