Multiparametric analysis of CD8+ T cell compartment phenotype in chronic lymphocytic leukemia reveals a signature associated with progression toward therapy

CD8+ T cells are frontline defenders against cancer and primary targets of current immunotherapies. In CLL, specific functional alterations have been described in circulating CD8+ T cells, yet a global view of the CD8+ T cell compartment phenotype and of its real impact on disease progression is pre...

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Detalhes bibliográficos

Principais autores:	Pauline Gonnord, Manon Costa, Arnaud Abreu, Michael Peres, Loïc Ysebaert, Sébastien Gadat, Salvatore Valitutti
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2019-04-01
coleção:	OncoImmunology
Assuntos:	cd8+ t cells multidimensional phenotyping chronic lymphocytic leukemia phenotypic signature supervised learning
Acesso em linha:	http://dx.doi.org/10.1080/2162402X.2019.1570774
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