Cyclization increases bactericidal activity of arginine-rich cationic cell-penetrating peptide for Neisseria gonorrhoeae

ABSTRACT We previously reported that a linear cationic 12-amino acid cell-penetrating peptide (CPP) was bactericidal for Neisseria gonorrhoeae. In this study, our objectives were to determine the effect of cyclization of the linear CPP on its antibacterial activity for N. gonorrhoeae and cytotoxicit...

Descripción completa

Detalles Bibliográficos

Autores principales:	Constance M. John, Suzanne A. Otala, Gary A. Jarvis
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology 2024-09-01
Colección:	Microbiology Spectrum
Materias:	Neisseria gonorrhoeae gonorrhea cell-penetrating peptides bactericidal activity lipooligosaccharide sialic acid
Acceso en línea:	https://journals.asm.org/doi/10.1128/spectrum.00997-24
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!